Systems biology is an interdisciplinary search for the fundamental organizing principles that underlie the evolution and function of biological systems ranging from small molecular networks to multi-species communities. The related field of genomics aims to understand the structure, function, and evolution of genomes, using large-scale genetic and molecular observations. Computational, statistical, and theoretical approaches are fundamental to genomics and systems biology. Large-scale molecular and phenotypic observations, coupled with theory and artificial intelligence, enable systems biologists to develop predictive understanding of biological behavior and reveal the key organizing principles that are often obscured by the underlying descriptive details. By harnessing the power of genomics and systems biology, researchers can uncover new biological insights, advance our knowledge of the fundamental processes that govern life, and help develop novel therapeutic approaches.
Research Groups
Andolfatto Lab
The evolutionary processes shaping genome evolution and the genetic mechanisms underlying adaptations and species-specific traits
Bussemaker Lab
Data-driven predictive modeling of gene regulatory networks
Dietrich Lab
Bacterial models for biological shape and pattern formation
Gaublomme Lab
Create and apply multi-omic technologies to study biomolecular and cellular interactions during development, physiology and pathology
Jovanovic Lab
Regulation of protein production dynamics: RNA binding proteins and the ribosome code
Landweber Lab
RNA-mediated epigenetics and genome reorganization during development
Przeworski Lab
Population and human genetics
Sella Lab
Evolutionary and population genetics of adaptation and disease
Tavaré Lab
Computational cancer genomics, including statistical and stochastic methods for understanding tumor heterogeneity and cancer evolution
Tavazoie Lab
Principles of cellular adaptation
Tomer Lab
Develop and apply molecular, optical and data analytic methods for multi-scale understanding of complex biological systems
Tosches Lab
Evolution of cell types and circuits in the vertebrate brain
