Seminar - Geraldine Seydoux

photo of Geraldine Seydoux
March 2, 2020 - 12:00pm
Location: 
601 Fairchild

Johns Hopkins University, School of Medicine

Host: Iva Greenwald

Title: Regulation of RNA granule assembly by intrinsically-disordered proteins

Abstract: RNA granules are RNA/protein condensates that form in the cytoplasm or nucleoplasm of cells. My laboratory studies the assembly and function of P granules, RNA granules in the germline of C. elegans. I will present evidence that P granule assembly is driven by condensation of mRNAs with intrinsically-disordered proteins that form nanoscale gels. Our findings suggest that RNA-protein gels may be a common strategy to co-localize and segregate large numbers of mRNAs in cells.

Business Office

Department of Biological Sciences
500 Fairchild Center
Mail Code 2401
Columbia University
1212 Amsterdam Avenue
New York, NY 10027

Academic Office

Department of Biological Sciences
600 Fairchild Center
Mail Code 2402
Columbia University
1212 Amsterdam Avenue
New York, NY 10027
biology@columbia.edu
212 854-4581