BIOL
W4510
Molecular Systems Biology
Semester: 
Spring 2014
Section Number: 
001
Days of the Week: 
Mondays
Time: 
2:40pm - 5:25pm
Number of Credits: 
4
Course Description: 

Prerequisites: One year of Biology and Chemistry required; Physics recommended. Courses taken at CU are preferred, but AP courses may be sufficient with permission from the instructor. This course will provide students with a quantitative understanding of the ways in which molecular interactions between nucleotides and proteins give rise to the behavior of gene regulatory networks. The key high-throughput genomics technologies for probing the cell at different levels using microarrays and next-generation sequencing will be discussed. Strategies for interpreting and integrating these data using statistics, biophysics and genetics will be introduced. In computer exercises, student will learn the basics of the R language, and use it to perform analyses of genomics data sets. No prior computer programming experience is assumed. This highly interdisciplinary course is intended for advanced undergraduates as well as beginning graduate students in Biology, Chemistry, Physics, Engineering, and Computer Science. 

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Department of Biological Sciences
600 Fairchild Center
Mail Code 2402
Columbia University
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biology@columbia.edu
212 854-4581